Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | DDT | P30046 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.38 |
| ▸ | FNTB | P49356 | 2/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572761 | 0.87 | ALDH1A1 (0.42) | FOLH1MAP4K4PTGDR2KDM4CRXRA | |
| SCHEMBL6571107 | 0.85 | KDM4C (0.40) | KMOFOLH1PLA2G2AKDM4CFNTA | |
| SCHEMBL6574565 | 0.85 | MAPT (0.40) | MAP4K4PTGDR2 | |
| Hydrochloric Acid SCHEMBL6572997 | 0.83 | PTGDR2 (0.43) | PTGDR2 | |
| SCHEMBL6572182 | 0.81 | PIK3CG (0.41) | MAP4K4PTGDR2 | |
| SCHEMBL6572172 | 0.80 | STK4 (0.45) | — | |
| SCHEMBL6572491 | 0.80 | MAPT (0.37) | PTGDR2 | |
| SCHEMBL6570856 | 0.80 | ALDH1A1 (0.38) | MAP4K4PTGDR2 | |
| SCHEMBL6572058 | 0.80 | TAAR1 (0.45) | MAP4K4PTGDR2 | |
| SCHEMBL6570947 | 0.80 | TRIM24 (0.37) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |