SCHEMBL6573345

SCHEMBL6573345

[O]C(Cc1ccccc1)C([O])(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
LMNA P02545 1/20 0.43
MAPK1 P28482 1/20 0.43
CYP1A2 P05177 2/20 0.42
EPHX1 P07099 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ALPI P09923 1/20 0.39
PKM P14618 1/20 0.39
PTGS1 P23219 1/20 0.39
XIAP P98170 1/20 0.39
SLC7A5 Q01650 1/20 0.39
SLC6A2 P23975 2/20 0.39
TAAR1 Q96RJ0 2/20 0.39
MAOA P21397 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
CYP2A6 P11509 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8050764 0.74 TRPA1 (0.47) CYP1A2EPHX1ALPIPKMPTGS1
SCHEMBL5609280 0.74 CPA1 (0.46) CYP1A2EPHX1ALPIPKMPTGS1
SCHEMBL10514103 0.72 EPHX1 (0.52) CYP1A2EPHX1ALPIPKMPTGS1
SCHEMBL1287175 0.70 EPHX1 (0.50) CYP1A2EPHX1ALPIPKMPTGS1
SCHEMBL7897856 0.70 CYP1A2 (0.45) CYP1A2EPHX1ALPIPKMPTGS1
SCHEMBL11741416 0.69 EPHX1 (0.55) CYP1A2EPHX1ALPIPKMPTGS1
SCHEMBL1833632 0.69 EPHX1 (0.55) CYP1A2EPHX1ALPIPKMPTGS1
SCHEMBL11327689 0.69 CYP2D6 (0.42) MAPK1CYP1A2TAAR1CYP2C19CYP2D6
SCHEMBL8864309 0.67 NPSR1 (0.42) KDM4ELMNAMAPK1CYP1A2EPHX1
SCHEMBL4274915 0.67 SRC (0.38) LMNAMAPK1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0970964-B1 Method for producing a titanium complex SUMITOMO CHEMICAL CO (JP) 2004-04-21 EP disclosed
US-6090961-A Method for producing titanium complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-07-18 US disclosed
EP-0970964-A2 Method for producing titanium complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-01-12 EP disclosed