Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918305 | 0.83 | PTPN1 (0.43) | PTPN1FAAHTACR3 | |
| SCHEMBL6574928 | 0.79 | PTPN1 (0.59) | PTPN1 | |
| SCHEMBL6573397 | 0.79 | PTPN1 (0.59) | PTPN1 | |
| SCHEMBL6804095 | 0.79 | MME (0.43) | PTPN1FAAHTACR3 | |
| SCHEMBL6918302 | 0.75 | TACR3 (0.48) | TACR3 | |
| SCHEMBL6575310 | 0.74 | PTPN1 (0.49) | ITGB3ITGA2BCCKBRPTPN1 | |
| SCHEMBL6575538 | 0.73 | SRD5A2 (0.45) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL6572344 | 0.73 | PTPN1 (0.62) | PTPN1 | |
| SCHEMBL6571434 | 0.73 | PTPN1 (0.62) | PTPN1 | |
| SCHEMBL6571438 | 0.73 | PTPN1 (0.62) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353023-B1 | AROMATIC COMPOUNDS WITH AMIDE GROUPS | PHARMACIA & UPJOHN COMPANY | 2002-03-05 | — | — | US | claimed |
| EP-1019364-B1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2004-06-09 | — | — | EP | disclosed |
| US-6410585-B1 | THERAPY FOR NON-INSULIN DEPEND DIABETES | BIOVITRUM AB (SE) | 2002-06-25 | — | — | US | disclosed |
| US-6353023-B1 | AROMATIC COMPOUNDS WITH AMIDE GROUPS | PHARMACIA & UPJOHN COMPANY | 2002-03-05 | — | — | US | disclosed |