Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | LTA | P01374 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.37 |
| ▸ | RAD1 | O60671 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bitoscanate SCHEMBL157128 | 0.82 | MIF (0.72) | MIFP2RY6CA1CA2HSD17B10 | |
| SCHEMBL7562305 | 0.80 | CYP3A4 (0.56) | P2RY6CA1CA2CYP3A4ALDH1A1 | |
| SCHEMBL331404 | 0.80 | MIF (0.56) | MIFP2RY6CA1CA2HSD17B10 | |
| SCHEMBL786739 | 0.76 | MIF (0.52) | MIFP2RY6CA1CA2HSD17B10 | |
| SCHEMBL27662495 | 0.76 | MIF (0.52) | MIFP2RY6CA1CA2HSD17B10 | |
| SCHEMBL28228359 | 0.75 | MIF (0.56) | MIFP2RY6CA1CA2HSD17B10 | |
| SCHEMBL29088588 | 0.74 | P2RY6 (0.50) | MIFP2RY6CA1CA2HSD17B10 | |
| SCHEMBL1548531 | 0.74 | MIF (0.62) | MIFP2RY6CA1CA2HSD17B10 | |
| Bitoscanate SCHEMBL8443297 | 0.73 | CA1 (0.63) | MIFP2RY6CA1CA2HSD17B10 | |
| SCHEMBL2217784 | 0.73 | MIF (0.67) | MIFP2RY6CA1CA2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816364-B1 | Reagents for lysergic acid diethylamide immunoassay | HOFFMANN LA ROCHE (CH) | 2004-01-02 | — | — | EP | claimed |
| WO-2003047515-A2 | P2X7 RECEPTOR ANTAGONISTS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-06-12 | — | — | WO | claimed |
| EP-0220899-B1 | BIFUNCTIONAL LINKER | Immunomedics, Inc. (US) | 1992-03-11 | — | — | EP | claimed |
| WO-2003047515-A2 | P2X7 RECEPTOR ANTAGONISTS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-06-12 | — | — | WO | disclosed |
| US-5013547-A | Anticancer drug - antibody conjugates and method for preparing same | ERBAMONT, INC. (US) | 1991-05-07 | — | — | US | disclosed |