Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531243 | 0.83 | CYP19A1 (0.42) | CYP19A1EPHX2VNN1NSD2MAOA | |
| SCHEMBL9192710 | 0.83 | CYP19A1 (0.45) | CYP19A1EPHX2VNN1PTGDR2EGFR | |
| SCHEMBL8410915 | 0.77 | CYP19A1 (0.47) | CYP19A1EPHX2VNN1MAOAMAOB | |
| SCHEMBL28206880 | 0.75 | AOC3 (0.40) | KDM4E | |
| SCHEMBL9193083 | 0.75 | EPHX2 (0.45) | CYP19A1EPHX2VNN1PTGDR2NSD2 | |
| SCHEMBL9196854 | 0.74 | CYP19A1 (0.40) | CYP19A1EPHX2VNN1PTGDR2MAOA | |
| SCHEMBL19329955 | 0.74 | EPHX2 (0.44) | CYP19A1EPHX2PTGDR2NSD2MAOA | |
| SCHEMBL20838414 | 0.74 | EPHX2 (0.44) | CYP19A1EPHX2PTGDR2NSD2MAOA | |
| SCHEMBL8408994 | 0.73 | CYP19A1 (0.45) | CYP19A1EPHX2VNN1PTGDR2 | |
| SCHEMBL8408717 | 0.72 | CYP19A1 (0.43) | CYP19A1EPHX2VNN1NSD2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399158-A1 | AROMATASE INHIBITORS AS NOVEL VETERINARY DRUGS | Vetcare Oy (FI) | 2004-03-24 | — | — | EP | claimed |
| WO-2002087571-A1 | AROMATASE INHIBITORS AS NOVEL VETERINARY DRUGS | VETCARE OY (FI) | 2002-11-07 | — | — | WO | claimed |