Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191168 | 0.80 | CYP19A1 (0.42) | CYP19A1MAOAMAOBEPHX2EGFR | |
| SCHEMBL6573450 | 0.74 | CYP19A1 (0.41) | CYP19A1MAOAMAOBEPHX2EGFR | |
| SCHEMBL9192710 | 0.72 | CYP19A1 (0.45) | CYP19A1EPHX2EGFRVNN1PTGDR2 | |
| SCHEMBL9192319 | 0.72 | CYP19A1 (0.45) | CYP19A1EPHX2EGFRPTGDR2 | |
| SCHEMBL9193083 | 0.71 | EPHX2 (0.45) | CYP19A1EPHX2VNN1KDM4EPTGDR2 | |
| SCHEMBL8410909 | 0.68 | CYP19A1 (0.54) | CYP19A1EPHX2 | |
| SCHEMBL8408994 | 0.68 | CYP19A1 (0.45) | CYP19A1EPHX2VNN1PTGDR2 | |
| SCHEMBL9196242 | 0.67 | CYP19A1 (0.36) | CYP19A1MAOAMAOBEPHX2VNN1 | |
| SCHEMBL6526163 | 0.66 | CYP19A1 (0.41) | CYP19A1MAOBKDM4E | |
| SCHEMBL6531243 | 0.66 | CYP19A1 (0.42) | CYP19A1MAOAMAOBEPHX2VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674626-A1 | NOVEL SELECTIVE AROMATASE INHIBITING COMPOUNDS | ORION-YHTYMÄ OY (FI) | 1995-10-04 | — | — | EP | claimed |