Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 9/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 9/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 9/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 9/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 9/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 9/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | RORA | P35398 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | RORB | Q92753 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17775036 | 0.87 | PGR (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL17775031 | 0.87 | PGR (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL17775032 | 0.87 | PGR (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL15667726 | 0.85 | PGR (0.58) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL17760825 | 0.80 | PGR (0.56) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL750975 | 0.80 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1001993 | 0.80 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6275417 | 0.80 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1000878 | 0.80 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6774209 | 0.80 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453802-A1 | 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF | THE UNIVERSITY OF SHEFFIELD (GB) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050086-A1 | 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF | THE UNIVERSITY OF SHEFFIELD (GB) | 2003-06-19 | — | — | WO | disclosed |