Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631077 | 0.83 | MAPT (0.50) | MAPTMEN1KMT2AGPR84CYP3A4 | |
| SCHEMBL290807 | 0.82 | GPR84 (0.53) | MAPTMEN1KMT2AGPR84CYP3A4 | |
| SCHEMBL18498486 | 0.81 | MEN1 (0.59) | MAPTMEN1KMT2AGPR84CYP3A4 | |
| SCHEMBL8850529 | 0.80 | MEN1 (0.61) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2124899 | 0.80 | MAPT (0.54) | MAPTMEN1KMT2AGPR84CYP3A4 | |
| SCHEMBL13735764 | 0.77 | POLB (0.50) | MAPTMEN1KMT2AGPR84CYP3A4 | |
| SCHEMBL1395865 | 0.77 | MAPT (0.62) | MAPTMEN1KMT2AGPR84CYP3A4 | |
| Indole-3-Acetic Acid SCHEMBL27576118 | 0.77 | MEN1 (0.55) | MAPTMEN1KMT2AGPR84CYP3A4 | |
| SCHEMBL7621032 | 0.76 | KMT2A (0.48) | MAPTKMT2APKMLMNAKDM4E | |
| SCHEMBL7613223 | 0.76 | HDAC3 (0.48) | MEN1KMT2ALMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409540-A2 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002026774-A2 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2002-04-04 | — | — | WO | disclosed |