Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 10/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788764 | 0.81 | MAPT (0.66) | CSNK2A1CYP3A4TSHRKDM4EMEN1 | |
| SCHEMBL27957341 | 0.81 | CSNK2A1 (0.44) | CSNK2A1CYP3A4TSHRKDM4EMEN1 | |
| SCHEMBL29610719 | 0.81 | S1PR4 (0.46) | CSNK2A1CYP3A4TSHRKDM4EMEN1 | |
| SCHEMBL6819499 | 0.81 | S1PR4 (0.46) | CSNK2A1CYP3A4TSHRKDM4EMEN1 | |
| SCHEMBL895104 | 0.81 | S1PR4 (0.58) | CYP3A4TSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11708436 | 0.80 | TP53 (0.47) | CSNK2A1CYP3A4TSHRKDM4EMEN1 | |
| SCHEMBL3788715 | 0.80 | SMN1; SMN2 (0.65) | CSNK2A1CYP3A4TSHRKDM4EMEN1 | |
| SCHEMBL3441850 | 0.80 | S1PR4 (0.50) | CSNK2A1CYP3A4TSHRKDM4EMEN1 | |
| SCHEMBL2000918 | 0.79 | KDM4E (0.54) | TSHRKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL3857536 | 0.78 | MAOA (0.57) | CSNK2A1CYP3A4TSHRKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775689-B9 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2004-09-15 | — | — | EP | disclosed |
| CN-1134410-C | Amine derivatives, process for their preparation and their use as antiarrhythmic agents | �й�ʯ����������ʯ�ͻ����������ι� | 2004-01-14 | — | — | CN | disclosed |
| EP-0775689-B1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2003-09-03 | — | — | EP | disclosed |
| US-6057358-A | POTASSIUM CHANNEL BLOCKING ANTIARRHYTHMIC DRUGS WITH LESS SIDE EFFECTS | C&C RESEARCH LABS. (KR) | 2000-05-02 | — | — | US | disclosed |
| CN-1169141-A | Novel amine derivatives, process for their preparation and their use as antiarrhythmic agents | C & C RESEARCH LABS (KR) | 1997-12-31 | — | — | CN | disclosed |
| EP-0775689-A1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RESEARCH LABS. (KR) | 1997-05-28 | — | — | EP | disclosed |