Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.56 |
| ▸ | PPARG | P37231 | 10/20 | 0.56 |
| ▸ | PPARD | Q03181 | 2/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576323 | 0.93 | PPARA (0.59) | PPARAPPARGPPARDACECTSK | |
| SCHEMBL6575413 | 0.87 | PPARA (0.73) | PPARAPPARGPPARDACE | |
| SCHEMBL6574106 | 0.87 | PPARA (0.73) | PPARAPPARGPPARDACE | |
| SCHEMBL8447233 | 0.82 | ACE (0.53) | ACE | |
| SCHEMBL6575597 | 0.82 | PPARA (0.57) | PPARAPPARGPPARDCTSKCTSS | |
| SCHEMBL9956138 | 0.80 | ACE (0.60) | PPARAPPARGPPARDACECTSK | |
| SCHEMBL3812722 | 0.80 | ACE (0.60) | PPARAPPARGPPARDACECTSK | |
| SCHEMBL3812726 | 0.80 | ACE (0.60) | PPARAPPARGPPARDACECTSK | |
| SCHEMBL8450418 | 0.78 | PPARA (0.70) | PPARAPPARGPPARDACE | |
| SCHEMBL6576315 | 0.78 | PPARA (0.60) | PPARAPPARGPPARDACECTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870762-B1 | NOVEL AMINO ACID DERIVATIVES HAVING N,N-DIALKYLAMINOPHENYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2004-04-28 | — | — | EP | disclosed |
| US-5872281-A | COMPOUNDS FOR TREATMENT OF RHEUMATIC DISEASES, PSORIASIS, INTESTINAL INFLAMATION | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0870762-A1 | NOVEL AMINO ACID DERIVATIVES HAVING N,N-DIALKYLAMINOPHENYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |