Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8454004 | 0.93 | ACE (0.56) | ACEFOLH1 | |
| SCHEMBL8447630 | 0.87 | ACE (0.69) | ACE | |
| SCHEMBL8453551 | 0.84 | ACE (0.43) | ACEFOLH1 | |
| SCHEMBL6574034 | 0.82 | PPARA (0.56) | ACE | |
| SCHEMBL8446649 | 0.82 | ACE (0.41) | ACEFOLH1 | |
| SCHEMBL6574069 | 0.79 | ACE (0.57) | ACE | |
| SCHEMBL8447649 | 0.79 | ACE (0.57) | ACE | |
| SCHEMBL8449770 | 0.78 | ACE (0.43) | ACEFOLH1 | |
| SCHEMBL6578261 | 0.78 | ACE (0.57) | ACE | |
| SCHEMBL8450604 | 0.78 | ACE (0.57) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872281-A | COMPOUNDS FOR TREATMENT OF RHEUMATIC DISEASES, PSORIASIS, INTESTINAL INFLAMATION | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-02-16 | — | — | US | disclosed |