Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.54 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | LCK | P06239 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519244 | 1.00 | TRPV1 (0.54) | TRPV1KDM6BHSD17B10MEN1KMT2A | |
| SCHEMBL29652186 | 0.99 | TRPV1 (0.56) | TRPV1KDM6BHSD17B10MEN1KMT2A | |
| SCHEMBL31268016 | 0.99 | TRPV1 (0.56) | TRPV1KDM6BHSD17B10MEN1KMT2A | |
| SCHEMBL31028433 | 0.96 | KDM6B (0.51) | TRPV1KDM6BHSD17B10MEN1KMT2A | |
| SCHEMBL29926699 | 0.96 | KDM6B (0.51) | TRPV1KDM6BHSD17B10MEN1KMT2A | |
| SCHEMBL31757523 | 0.92 | MAPT (0.56) | TRPV1HSD17B10MEN1KMT2AMAPT | |
| SCHEMBL22364280 | 0.90 | KDM6B (0.54) | TRPV1KDM6BHSD17B10MEN1KMT2A | |
| SCHEMBL29759443 | 0.90 | KDM6B (0.54) | TRPV1KDM6BHSD17B10MEN1KMT2A | |
| SCHEMBL31398395 | 0.86 | TRPV1 (0.54) | TRPV1KDM6BHSD17B10MEN1KMT2A | |
| SCHEMBL4850535 | 0.85 | FOLH1 (0.51) | MMEACECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864041-A | REACTING N-ACYL-3,4-DIHYDROXYPHENYLALAMINE DERIVATIVE WITH A HALOGEN RADICAL GENERATOR, A CERIUM SALT IN PRESENCE OR ABSENCE OF COPPER SALT CATALYST, OR A PERSULFATE SALT WITH COPPER CATALYST; USEFUL FOR TREATING NERVOUS SYSTEM DISORDERS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1999-01-26 | — | — | US | claimed |
| US-5739387-A | CATALYTIC CYCLIZATION WITH A CERIUM SALT OR A PERSULFATE SALT, DECYCLIZATION, DEBLOCKING AND DEPROTECTING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | claimed |
| JP-9031038-A | — | — | None | — | — | JP | disclosed |
| EP-1019364-B1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2004-06-09 | — | — | EP | disclosed |
| US-6410585-B1 | THERAPY FOR NON-INSULIN DEPEND DIABETES | BIOVITRUM AB (SE) | 2002-06-25 | — | — | US | disclosed |
| US-6353023-B1 | AROMATIC COMPOUNDS WITH AMIDE GROUPS | PHARMACIA & UPJOHN COMPANY | 2002-03-05 | — | — | US | disclosed |
| EP-1019364-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999011606-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-11 | — | — | WO | disclosed |
| US-5864041-A | REACTING N-ACYL-3,4-DIHYDROXYPHENYLALAMINE DERIVATIVE WITH A HALOGEN RADICAL GENERATOR, A CERIUM SALT IN PRESENCE OR ABSENCE OF COPPER SALT CATALYST, OR A PERSULFATE SALT WITH COPPER CATALYST; USEFUL FOR TREATING NERVOUS SYSTEM DISORDERS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5739387-A | CATALYTIC CYCLIZATION WITH A CERIUM SALT OR A PERSULFATE SALT, DECYCLIZATION, DEBLOCKING AND DEPROTECTING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |
| JP-H0931038-A | OXAZOLINES, THEIR PRODUCTION AND PRODUCTION OF THREO-3-(3,4-DIHYDROXYPHENYL)SERINE | SUMITOMO CHEM CO LTD | 1997-02-04 | — | — | JP | disclosed |