Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | RECQL | P46063 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | LCK | P06239 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29759443 | 1.00 | KDM6B (0.54) | KDM6BKDM4EHSD17B10ALOX15HIF1A | |
| SCHEMBL29926699 | 0.92 | KDM6B (0.51) | KDM6BKDM4EHSD17B10ALOX15HIF1A | |
| SCHEMBL31028433 | 0.92 | KDM6B (0.51) | KDM6BKDM4EHSD17B10ALOX15HIF1A | |
| SCHEMBL8519244 | 0.90 | TRPV1 (0.54) | KDM6BKDM4EHSD17B10ALOX15HIF1A | |
| SCHEMBL6574091 | 0.90 | TRPV1 (0.54) | KDM6BKDM4EHSD17B10ALOX15HIF1A | |
| SCHEMBL29652186 | 0.89 | TRPV1 (0.56) | KDM6BKDM4EHSD17B10ALOX15HIF1A | |
| SCHEMBL31268016 | 0.89 | TRPV1 (0.56) | KDM6BKDM4EHSD17B10ALOX15HIF1A | |
| SCHEMBL7433937 | 0.88 | KDM6B (0.57) | KDM6BKDM4EHSD17B10ALOX15HIF1A | |
| SCHEMBL22364281 | 0.88 | KDM6B (0.57) | KDM6BKDM4EHSD17B10ALOX15HIF1A | |
| SCHEMBL29700186 | 0.88 | KDM6B (0.57) | KDM6BKDM4EHSD17B10ALOX15HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241062-A1 | THERAPEUTIC DRUG FOR MOTOR COMPLICATIONS IN PARKINSON'S DISEASE | SUMITOMO PHARMA CO LTD (JP) | 2023-08-03 | — | — | US | disclosed |
| EP-4218764-A1 | THERAPEUTIC AGENT FOR MOTOR COMPLICATIONS IN PARKINSON'S DISEASE | Sumitomo Pharma Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |
| US-20230201199-A1 | THERAPEUTIC DRUG FOR DYSKINESIA | SUMITOMO PHARMA CO LTD (JP) | 2023-06-29 | — | — | US | disclosed |
| US-11628169-B2 | Therapeutic drug for motor complications in Parkinson's disease | Sumitomo Pharma Co., Ltd. (JP) | 2023-04-18 | — | — | US | disclosed |
| US-20220193075-A1 | THERAPEUTIC DRUG FOR DYSKINESIA | Sumitomo Pharma Co., Ltd. (JP) | 2022-06-23 | — | — | US | disclosed |
| US-20210386739-A1 | THERAPEUTIC DRUG FOR DYSKINESIA | Sumitomo Pharma Co., Ltd. (JP) | 2021-12-16 | — | — | US | disclosed |
| US-20210060015-A1 | THERAPEUTIC DRUG FOR DYSKINESIA | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-03-04 | — | — | US | disclosed |
| WO-2020218487-A1 | THERAPEUTIC DRUG FOR DYSKINESIA | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-10-29 | — | — | WO | disclosed |
| US-10758535-B1 | Therapeutic drug for dyskinesia | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230241062-A1 | THERAPEUTIC DRUG FOR MOTOR COMPLICATIONS IN PARKINSON'S DISEASE | PARK7, SNCA, SMN1; SMN2 | KDM6B 4439/4885KDM4E 4497/4885HSD17B10 1733/4885 |
| US-20230201199-A1 | THERAPEUTIC DRUG FOR DYSKINESIA | PARK7, SLC6A3, SNCA | KDM6B 4125/4885KDM4E 4084/4885HSD17B10 356/4885 |
| US-20210060015-A1 | THERAPEUTIC DRUG FOR DYSKINESIA | PARK7, SLC6A3, SNCA | KDM6B 4145/4885KDM4E 4139/4885HSD17B10 371/4885 |
| US-10758535-B1 | Therapeutic drug for dyskinesia | PARK7, SLC6A3, SNCA | KDM6B 4145/4885KDM4E 4139/4885HSD17B10 371/4885 |
| US-20210386739-A1 | THERAPEUTIC DRUG FOR DYSKINESIA | PARK7, SLC6A3, SNCA | KDM6B 4125/4885KDM4E 4084/4885HSD17B10 356/4885 |
| US-11628169-B2 | Therapeutic drug for motor complications in Parkinson's disease | PARK7, SNCA, SMN1; SMN2 | KDM6B 4439/4885KDM4E 4497/4885HSD17B10 1733/4885 |
| US-20220193075-A1 | THERAPEUTIC DRUG FOR DYSKINESIA | PARK7, SLC6A3, SNCA | KDM6B 4145/4885KDM4E 4139/4885HSD17B10 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.