⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3021981 | 0.72 | — | — | |
| SCHEMBL18126118 | 0.69 | — | — | |
| SCHEMBL3762454 | 0.68 | TSHR (0.33) | — | |
| SCHEMBL6574129 | 0.67 | — | — | |
| SCHEMBL271044 | 0.65 | — | — | |
| SCHEMBL13450 | 0.65 | — | — | |
| SCHEMBL7186086 | 0.65 | TSHR (0.46) | — | |
| SCHEMBL4047835 | 0.65 | LMNA (0.39) | — | |
| SCHEMBL9292 | 0.64 | — | — | |
| SCHEMBL18672378 | 0.64 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840741-B1 | PNA-DNA CHIMERAS AND PNA SYNTHONS FOR THEIR PREPARATION | PERSEPTIVE BIOSYSTEMS INC (US) | 2004-04-28 | — | — | EP | claimed |
| JP-2001518054-A | — | — | 2001-10-09 | — | — | JP | claimed |
| EP-0840741-A1 | PNA-DNA CHIMERAS AND PNA SYNTHONS FOR THEIR PREPARATION | PERSEPTIVE BIOSYSTEMS, INC. (US) | 1998-05-13 | — | — | EP | claimed |
| WO-1996040709-A1 | PNA-DNA CHIMERAS AND PNA SYNTHONS FOR THEIR PREPARATION | PERSEPTIVE BIOSYSTEMS, INC. (US) | 1996-12-19 | — | — | WO | claimed |