Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.54 |
| ▸ | PPARD | Q03181 | 10/20 | 0.54 |
| ▸ | PPARG | P37231 | 11/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5578931 | 1.00 | PPARA (0.54) | PPARAPPARDPPARGKDM4EGAA | |
| SCHEMBL5579015 | 0.89 | PPARA (0.56) | PPARAPPARDPPARGKDM4EGAA | |
| SCHEMBL5578935 | 0.76 | PPARG (0.45) | PPARAPPARDPPARG | |
| SCHEMBL5377399 | 0.75 | PPARA (0.68) | PPARAPPARDPPARG | |
| SCHEMBL5394941 | 0.75 | PPARA (0.68) | PPARAPPARDPPARG | |
| SCHEMBL5037444 | 0.71 | PIN1 (0.45) | KDM4EGAASMN1; SMN2 | |
| SCHEMBL5037447 | 0.71 | PIN1 (0.45) | KDM4EGAASMN1; SMN2 | |
| SCHEMBL16933420 | 0.70 | POLB (0.46) | KDM4ESMN1; SMN2 | |
| SCHEMBL28421404 | 0.70 | PIN1 (0.50) | PPARASMN1; SMN2 | |
| SCHEMBL5385890 | 0.70 | PPARA (0.50) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392637-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100813-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |