SCHEMBL6574271

SCHEMBL6574271

CCOC1CCCC1C=O

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPK1 P28482 1/20 0.32
ADH1C P00326 2/20 0.31
ADH1A P07327 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6576261 0.96 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2MAPK1ADH1CADH1A
SCHEMBL6575898 0.87
SCHEMBL19227974 0.80
SCHEMBL20995934 0.77 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2MAPK1
SCHEMBL24234514 0.76
SCHEMBL1922274 0.76
SCHEMBL6572114 0.76
SCHEMBL16131609 0.75 NPSR1 (0.30)
SCHEMBL7773656 0.73 CHRM2 (0.47) ALDH1A1
SCHEMBL21357944 0.71 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2497475-A1 Treatment of laminitis with platelet aggregation inhibitors Dussler, Sabine (DE) 2012-09-12 EP disclosed
EP-0934928-B1 CYCLIC AMINE DERIVATIVES SANKYO CO (JP) 2004-10-13 EP disclosed
US-6610708-B1 Anticoagulants SANKYO COMPANY, LIMITED (JP) 2003-08-26 US disclosed
EP-1063230-B1 CYCLIC AMINO COMPOUNDS SANKYO CO (JP) 2003-04-23 EP disclosed
EP-0765879-B1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests SANKYO CO (JP) 2001-02-14 EP disclosed
EP-1063230-A1 CYCLIC AMINO COMPOUNDS Sankyo Company Limited (JP) 2000-12-27 EP disclosed
US-6087379-A AN ANTICOAGULANT FOR THE TREATMENT AND PREVENTION OF DISEASES AS EMBOLISM, THROMBOSIS OR ARTERIOSCLEROSIS SANKYO COMPANY, LIMITED (JP) 2000-07-11 US disclosed
EP-0934928-A1 CYCLIC AMINE DERIVATIVES SANKYO COMPANY LIMITED (JP) 1999-08-11 EP disclosed
US-5861429-A MITICIDES AND ANTHELMINTICS SANKYO COMPANY, LIMITED (JP) 1999-01-19 US disclosed
EP-0765879-A1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests SANKYO COMPANY LIMITED (JP) 1997-04-02 EP disclosed
US-5436242-A Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof for inhibiting blood platelet aggregation SANKYO COMPANY, LIMITED (JP) 1995-07-25 US disclosed
US-5288726-A Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation UBE INDUSTRIES LIMITED (JP) 1994-02-22 US disclosed
EP-0542411-A2 Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation Sankyo Company Limited (JP) 1993-05-19 EP disclosed