Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994314 | 1.00 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7454579 | 1.00 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL2994310 | 1.00 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6572673 | 1.00 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL5304089 | 1.00 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7349039 | 1.00 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6574444 | 1.00 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6574466 | 1.00 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7343838 | 1.00 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7343843 | 1.00 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397358-A1 | TROPANE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002102801-A1 | TROPANE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2002-12-27 | — | — | WO | disclosed |