Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 13/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574492 | 0.96 | ADORA3 (0.57) | ADORA3ADORA2AADORA1ADORA2BMEN1 | |
| SCHEMBL6574215 | 0.94 | ADORA3 (0.49) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL6574213 | 0.90 | ADORA3 (0.51) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| Formic Acid SCHEMBL6574490 | 0.90 | ADORA3 (0.61) | ADORA3ADORA2AADORA1ADORA2BMEN1 | |
| Formic Acid SCHEMBL6574218 | 0.84 | ADORA3 (0.54) | ADORA3ADORA2AADORA1ADORA2BMEN1 | |
| SCHEMBL6573870 | 0.77 | ADORA3 (0.60) | ADORA3ADORA2AADORA1ADORA2BMEN1 | |
| SCHEMBL6573904 | 0.75 | ADORA3 (0.46) | ADORA3ADORA2AADORA1ADORA2BMEN1 | |
| SCHEMBL6576757 | 0.73 | ADORA3 (0.66) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL19100521 | 0.71 | ADORA3 (0.81) | ADORA3ADORA2AADORA1ADORA2BMEN1 | |
| SCHEMBL31339951 | 0.71 | ADORA3 (0.68) | ADORA3ADORA2AADORA1ADORA2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | disclosed |
| EP-1447407-A1 | Adenosine derivatives | GLAXO GROUP LIMITED (GB) | 2004-08-18 | — | — | EP | disclosed |