Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574561 | 1.00 | ADORA3 (0.47) | ADORA3ADORA1SLC29A1ADORA2AADORA2B | |
| SCHEMBL6575154 | 0.90 | SLC29A1 (0.47) | ADORA3ADORA1SLC29A1ADORA2AADORA2B | |
| SCHEMBL6575163 | 0.90 | SLC29A1 (0.47) | ADORA3ADORA1SLC29A1ADORA2AADORA2B | |
| SCHEMBL6802786 | 0.88 | SLC29A1 (0.45) | ADORA3ADORA1SLC29A1ADORA2AADORA2B | |
| SCHEMBL6576779 | 0.88 | SLC29A1 (0.45) | ADORA3ADORA1SLC29A1ADORA2AADORA2B | |
| SCHEMBL6576783 | 0.88 | SLC29A1 (0.45) | ADORA3ADORA1SLC29A1ADORA2AADORA2B | |
| SCHEMBL6575155 | 0.87 | ADORA3 (0.46) | ADORA3ADORA1SLC29A1ADORA2AADORA2B | |
| SCHEMBL6575157 | 0.87 | ADORA3 (0.46) | ADORA3ADORA1SLC29A1ADORA2AADORA2B | |
| SCHEMBL6574576 | 0.85 | ADORA3 (0.47) | ADORA3ADORA1SLC29A1ADORA2AADORA2B | |
| SCHEMBL6574580 | 0.85 | ADORA3 (0.47) | ADORA3ADORA1SLC29A1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | disclosed |
| EP-1447407-A1 | Adenosine derivatives | GLAXO GROUP LIMITED (GB) | 2004-08-18 | — | — | EP | disclosed |