Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 17/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574791 | 0.92 | P2RX7 (0.41) | P2RX7HDAC6LMNAEPHX2 | |
| SCHEMBL6574891 | 0.89 | P2RX7 (0.40) | P2RX7LMNAEPHX2 | |
| SCHEMBL6571362 | 0.87 | P2RX7 (0.41) | P2RX7HDAC6LMNAEPHX2 | |
| SCHEMBL6573153 | 0.87 | P2RX7 (0.39) | P2RX7LMNAEPHX2 | |
| SCHEMBL5077403 | 0.79 | P2RX7 (0.74) | P2RX7 | |
| SCHEMBL7570693 | 0.73 | P2RX7 (0.64) | P2RX7 | |
| Hydrochloric Acid SCHEMBL7573056 | 0.72 | P2RX7 (0.65) | P2RX7 | |
| SCHEMBL6572556 | 0.72 | P2RX7 (0.61) | P2RX7 | |
| SCHEMBL6371622 | 0.72 | P2RX7 (0.53) | P2RX7HDAC6 | |
| SCHEMBL6571934 | 0.71 | SCN9A (0.46) | P2RX7LMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240132-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-04-07 | — | — | EP | claimed |