Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597924 | 1.00 | FPR2 (0.49) | FPR2SLC6A2SLC6A3ACACBNOS2 | |
| SCHEMBL13572956 | 1.00 | FPR2 (0.49) | FPR2SLC6A2SLC6A3ACACBNOS2 | |
| SCHEMBL7716798 | 0.86 | ESR1 (0.46) | ALDH1A1ESR1ESR2CYP3A4CYP2C9 | |
| SCHEMBL15495960 | 0.86 | ESR1 (0.46) | ALDH1A1ESR1ESR2CYP3A4CYP2C9 | |
| SCHEMBL14884535 | 0.84 | CDK2 (0.44) | ESR1ESR2 | |
| SCHEMBL14884528 | 0.84 | CDK2 (0.44) | ESR1ESR2 | |
| SCHEMBL2551616 | 0.84 | EPHX2 (0.52) | SLC6A2SLC6A3PPARGPPARAALDH1A1 | |
| SCHEMBL7574933 | 0.84 | CYP1A2 (0.50) | L3MBTL1PPARGPPARAALDH1A1CYP3A4 | |
| SCHEMBL13534766 | 0.84 | ESR1 (0.47) | ACACBL3MBTL1PPARGPPARAALDH1A1 | |
| SCHEMBL14590363 | 0.84 | ATM (0.50) | ACACBL3MBTL1PPARGPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397358-A1 | TROPANE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002102801-A1 | TROPANE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2002-12-27 | — | — | WO | disclosed |