Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.55 |
| ▸ | PPARG | P37231 | 16/20 | 0.55 |
| ▸ | PPARD | Q03181 | 11/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5387869 | 0.92 | PPARA (0.63) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL5387587 | 0.92 | PPARA (0.63) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL6574322 | 0.88 | PPARA (0.70) | PPARAPPARGPPARD | |
| SCHEMBL5382491 | 0.85 | PPARA (0.76) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL14571496 | 0.85 | PPARA (0.61) | PPARAPPARGPPARDFFAR1MME | |
| SCHEMBL5377956 | 0.85 | PPARA (0.76) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL5379864 | 0.84 | PPARA (0.79) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL5386707 | 0.83 | PPARA (0.80) | PPARAPPARGPPARD | |
| SCHEMBL5382586 | 0.82 | PPARA (0.63) | PPARAPPARGPPARD | |
| SCHEMBL14392125 | 0.82 | PPARA (0.67) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392637-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100813-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |