Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.69 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657527 | 1.00 | CYP1B1 (0.82) | CYP1B1CYP1A2CYP1A1MEN1KMT2A | |
| SCHEMBL6913489 | 0.91 | CYP3A4 (0.74) | CYP1B1CYP1A2CYP1A1MEN1KMT2A | |
| SCHEMBL658562 | 0.91 | CYP1B1 (1.00) | CYP1B1CYP1A2CYP1A1MEN1KMT2A | |
| SCHEMBL658561 | 0.91 | CYP1B1 (1.00) | CYP1B1CYP1A2CYP1A1MEN1KMT2A | |
| SCHEMBL29639743 | 0.91 | CYP1B1 (1.00) | CYP1B1CYP1A2CYP1A1MEN1KMT2A | |
| SCHEMBL29805401 | 0.91 | CYP1B1 (1.00) | CYP1B1CYP1A2CYP1A1MEN1KMT2A | |
| SCHEMBL656428 | 0.87 | CYP1B1 (0.81) | CYP1B1CYP1A2CYP1A1MEN1KMT2A | |
| SCHEMBL656427 | 0.87 | CYP1B1 (0.81) | CYP1B1CYP1A2CYP1A1MEN1KMT2A | |
| SCHEMBL976912 | 0.85 | CYP1B1 (0.71) | CYP1B1CYP1A2CYP1A1MEN1KMT2A | |
| SCHEMBL12306205 | 0.85 | CYP1B1 (0.71) | CYP1B1CYP1A2CYP1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349999-B1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIV SAARLAND (DE) | 2016-01-27 | — | — | EP | disclosed |
| US-8912186-B2 | Allosteric protein kinase modulators | UNIVERSITAET DES SAARLANDES (DE) | 2014-12-16 | — | — | US | disclosed |
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2012-02-23 | — | — | US | disclosed |
| EP-2349999-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | Universität des Saarlandes (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010043711-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2010-04-22 | — | — | WO | disclosed |
| US-6762318-B2 | CARBOXYLIC ACID OR TETRAZOLE DERIVATIZED SECONDARY AMIDES; ORAL ADMINISTRATION | NOVO NORDISK A/S (DK) | 2004-07-13 | — | — | US | disclosed |
| US-20030236292-A1 | Stimulant releasing glucose from liver cells; antidiabetic agents | PFIZER INC | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236292-A1 | Stimulant releasing glucose from liver cells; antidiabetic agents | GPR119, GLP1R, GIPR | CYP1B1 3336/4885CYP1A2 2522/4885CYP1A1 2559/4885 |
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | AURKC, AURKA, AURKB | CYP1B1 4714/4885CYP1A2 4611/4885CYP1A1 4763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.