Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.47 |
| ▸ | FNTB | P49356 | 5/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PLEC | Q15149 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572503 | 0.85 | FNTA (0.42) | FNTAFNTBPGGT1BALDH1A1MAPT | |
| SCHEMBL6571846 | 0.85 | CYP1A2 (0.32) | FNTAFNTBPGGT1B | |
| SCHEMBL6574986 | 0.84 | BCHE (0.39) | FNTAFNTBPGGT1BALDH1A1THRB | |
| SCHEMBL6574373 | 0.83 | BCHE (0.40) | ADRB2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL6572113 | 0.83 | MAPT (0.36) | FNTAFNTBALDH1A1GAAMAPT | |
| SCHEMBL1664315 | 0.82 | FNTA (0.53) | FNTAFNTBPGGT1BADRB2ADRB1 | |
| SCHEMBL6572983 | 0.81 | FNTA (0.42) | FNTAFNTBPGGT1BKDM4EALDH1A1 | |
| SCHEMBL6571600 | 0.81 | FNTA (0.32) | FNTAFNTBPGGT1BMAPK14 | |
| SCHEMBL6573158 | 0.80 | ABL1 (0.33) | FNTAFNTBPGGT1B | |
| SCHEMBL6572130 | 0.80 | SYK (0.38) | ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |