Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.42 |
| ▸ | FNTB | P49356 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | GFER | P55789 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PLEC | Q15149 | 1/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572594 | 0.85 | PTGER4 (0.57) | FNTAFNTBMAP4K4KDM4EGFER | |
| SCHEMBL6572585 | 0.83 | ALDH1A1 (0.42) | FNTAFNTBMAP4K4KDM4EGAA | |
| SCHEMBL6572728 | 0.83 | FCGR3B (0.38) | MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL6572942 | 0.82 | APP (0.41) | KDM4EGFERGAAMAPTALDH1A1 | |
| SCHEMBL6575398 | 0.81 | FNTA (0.47) | FNTAFNTBMAP4K4KDM4EGFER | |
| SCHEMBL6572071 | 0.81 | NPC1 (0.39) | MAP4K4KDM4EGFERGAAMAPT | |
| SCHEMBL6572249 | 0.81 | MAPT (0.44) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL6574987 | 0.81 | MAP4K4 (0.43) | MAP4K4KDM4EGFERGAAMAPT | |
| SCHEMBL1663499 | 0.79 | TSHR (0.50) | FNTAFNTBALDH1A1KMT2AMEN1 | |
| SCHEMBL6571323 | 0.79 | ALDH1A1 (0.35) | KDM4EGAAMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |