SCHEMBL6575565

SCHEMBL6575565

CCCCC(CC)COC(=O)c1cc(C(=O)O)cc(C(=O)OCC(CC)CCCC)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
TSHR P16473 3/20 0.65
MAPK1 P28482 3/20 0.65
CYP3A4 P08684 4/20 0.61
LMNA P02545 3/20 0.61
HSD17B10 Q99714 1/20 0.61
CA2 P00918 1/20 0.61
PRSS1 P07477 1/20 0.55
PRSS2 P07478 1/20 0.55
PRSS3 P35030 1/20 0.55
TDP1 Q9NUW8 2/20 0.53
ATM Q13315 1/20 0.53
MAPT P10636 1/20 0.47
PRKCA P17252 1/20 0.45
PRKCD Q05655 1/20 0.45
RECQL P46063 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.41
ESR1 P03372 3/20 0.41
PLA2G2A P14555 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27359831 1.00 ALDH1A1 (0.65) ALDH1A1TSHRMAPK1CYP3A4LMNA
SCHEMBL6578078 0.94 ALDH1A1 (0.72) ALDH1A1TSHRMAPK1CYP3A4LMNA
SCHEMBL2532026 0.89 ALDH1A1 (0.67) ALDH1A1TSHRMAPK1CYP3A4LMNA
Isophthalic Acid SCHEMBL7186961 0.89 ALDH1A1 (0.67) ALDH1A1TSHRMAPK1CYP3A4LMNA
SCHEMBL7995097 0.88 ALDH1A1 (0.65) ALDH1A1TSHRMAPK1CYP3A4LMNA
SCHEMBL27255797 0.88 ALDH1A1 (0.65) ALDH1A1TSHRMAPK1CYP3A4LMNA
SCHEMBL12399287 0.88 PRSS1 (0.55) ALDH1A1TSHRMAPK1CYP3A4LMNA
SCHEMBL12860857 0.88 PRSS1 (0.55) ALDH1A1TSHRMAPK1CYP3A4LMNA
SCHEMBL108086 0.88 ALDH1A1 (0.73) ALDH1A1TSHRMAPK1CYP3A4LMNA
Isophthalic Acid SCHEMBL28378656 0.88 ALDH1A1 (0.65) ALDH1A1TSHRMAPK1CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1412082-A1 METHOD FOR HYDROGENATING ORGANIC COMPOUNDS BY MEANS OF RU/SIO2 CATALYSTS BASF Aktiengesellschaft (DE) 2004-04-28 EP disclosed
EP-1314714-A2 Method for hydrogenating benzene polycarboxylic acids or derivatives thereof by using a catalyst containing macropores BASF AKTIENGESELLSCHAFT (DE) 2003-05-28 EP disclosed
EP-1042273-B1 METHOD FOR HYDROGENATING BENZENE POLYCARBOXYLIC ACIDS OR DERIVATIVES THEREOF BY USING A CATALYST CONTAINING MACROPORES BASF AG (DE) 2003-05-07 EP disclosed
WO-2002100536-A1 METHOD FOR HYDROGENATING ORGANIC COMPOUNDS BY MEANS OF RU/SIO2 CATALYSTS BASF AKTIENGESELLSCHAFT (DE) 2002-12-19 WO disclosed
EP-1042273-A1 METHOD FOR HYDROGENATING BENZENE POLYCARBOXYLIC ACIDS OR DERIVATIVES THEREOF BY USING A CATALYST CONTAINING MACROPORES BASF AKTIENGESELLSCHAFT (DE) 2000-10-11 EP disclosed
WO-1999032427-A1 METHOD FOR HYDROGENATING BENZENE POLYCARBOXYLIC ACIDS OR DERIVATIVES THEREOF BY USING A CATALYST CONTAINING MACROPORES BASF AKTIENGESELLSCHAFT (DE) 1999-07-01 WO disclosed