Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575732 | 1.00 | THRB (0.36) | THRBMEN1KMT2A | |
| SCHEMBL6575735 | 1.00 | THRB (0.36) | THRBMEN1KMT2A | |
| Acetic Acid SCHEMBL7168511 | 0.89 | GRIN2D (0.32) | — | |
| SCHEMBL6544345 | 0.84 | CA1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL18864085 | 0.77 | THRB (0.31) | THRBMEN1KMT2A | |
| SCHEMBL2450711 | 0.76 | MEN1 (0.41) | THRBMEN1KMT2A | |
| SCHEMBL19370427 | 0.76 | MEN1 (0.41) | THRBMEN1KMT2A | |
| SCHEMBL18822225 | 0.76 | MEN1 (0.41) | THRBMEN1KMT2A | |
| SCHEMBL19056196 | 0.75 | THRB (0.32) | THRBMEN1KMT2A | |
| SCHEMBL19629166 | 0.74 | MEN1 (0.39) | THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140826-B1 | METHOD FOR PRODUCING (2S,4R,9S)-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID AND INTERMEDIATE PRODUCTS THEREFOR | ABBOTT GMBH & CO KG (DE) | 2004-05-06 | — | — | EP | disclosed |
| US-6559318-B1 | Hydrolysis of 1,1,3,3-tetraalkoxyalkane to 3,3-dialkoxypropionaldehyde using acid catalyst; Henry reaction with nitromethane; dehydration, Diels-Alder reaction, hydrogenation, cyanation, saponification | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-06 | — | — | US | disclosed |
| EP-1140826-A1 | METHOD FOR PRODUCING (2S,4R,9S)-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID AND INTERMEDIATE PRODUCTS THEREFOR | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040555-A1 | METHOD FOR PRODUCING (2S,4R,9S)-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID AND INTERMEDIATE PRODUCTS THEREFOR | BASF AKTIENGESELLSCHAFT (DE) | 2000-07-13 | — | — | WO | disclosed |