Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6250141 | 1.00 | KMT2A (0.62) | KMT2AMEN1LMNAMAPTGAA | |
| SCHEMBL6247195 | 0.93 | PTPN1 (0.57) | KMT2AMEN1LMNAMAPTGAA | |
| SCHEMBL3059437 | 0.80 | SLC7A5 (0.61) | KMT2AMEN1LMNAMAPTSLC7A5 | |
| SCHEMBL169645 | 0.80 | SLC7A5 (0.61) | KMT2AMEN1LMNAMAPTGAA | |
| SCHEMBL4943107 | 0.80 | SLC7A5 (0.61) | KMT2AMEN1LMNAMAPTSLC7A5 | |
| SCHEMBL169646 | 0.80 | SLC7A5 (0.61) | KMT2AMEN1LMNAMAPTGAA | |
| SCHEMBL30037334 | 0.80 | SLC7A5 (0.61) | KMT2AMEN1LMNAMAPTSLC7A5 | |
| SCHEMBL1932906 | 0.80 | SLC7A5 (0.61) | KMT2AMEN1LMNAMAPTGAA | |
| SCHEMBL21083181 | 0.79 | MAPT (0.57) | KMT2AMEN1LMNAMAPTGAA | |
| SCHEMBL2579208 | 0.78 | KMT2A (0.74) | KMT2AMEN1LMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040096906-A1 | Method for screening combinatorial bead library; ligands for cancer cells | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-05-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040096906-A1 | Method for screening combinatorial bead library; ligands for cancer cells | EPCAM, MKI67, FGFR3 | KMT2A 2986/4885MEN1 2334/4885LMNA 4112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.