Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.55 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5678587 | 0.88 | MAPT (0.59) | MAPTSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4943107 | 0.85 | SLC7A5 (0.61) | MAPTSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL30037334 | 0.85 | SLC7A5 (0.61) | MAPTSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3059437 | 0.85 | SLC7A5 (0.61) | MAPTSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL12835439 | 0.84 | ALDH1A1 (0.56) | MAPTSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL22689686 | 0.84 | SLC7A5 (0.56) | MAPTSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL22689687 | 0.84 | SLC7A5 (0.56) | MAPTSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7270611 | 0.84 | SLC7A5 (0.56) | MAPTSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL16860980 | 0.84 | SLC7A5 (0.56) | MAPTSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7270604 | 0.84 | SLC7A5 (0.56) | MAPTSLC7A5SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2605789-B1 | MODIFIED RELAXIN POLYPEPTIDES AND THEIR USES | AMBRX INC (US) | 2019-06-05 | — | — | EP | disclosed |