Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773891 | 0.85 | PRSS1 (0.59) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL6022670 | 0.85 | ALDH1A1 (0.65) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL6027275 | 0.84 | ALDH1A1 (0.50) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL3667882 | 0.83 | TSHR (0.58) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL6560805 | 0.82 | ALDH1A1 (0.62) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL659921 | 0.81 | ALDH1A1 (0.55) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL6561113 | 0.81 | ALDH1A1 (0.60) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL6561282 | 0.81 | ALDH1A1 (0.60) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL6561259 | 0.81 | ALDH1A1 (0.60) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL1919907 | 0.81 | TSHR (0.71) | TSHRTDP1L3MBTL1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046402-A1 | POLY LACTIC ACID-CONTAINING FILM OR SHEET, AND METHOD FOR MANUFACTURING THEREOF | NITTO DENKO CORPORATION (JP) | 2012-02-23 | — | — | US | disclosed |