Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | GRK2 | P25098 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11414383 | 0.92 | SMN1; SMN2 (0.59) | SMN1; SMN2CYP19A1HTTMEN1KMT2A | |
| SCHEMBL11418328 | 0.91 | RAB9A (0.58) | SMN1; SMN2CYP19A1HTTMEN1KMT2A | |
| SCHEMBL11419008 | 0.91 | RAB9A (0.58) | SMN1; SMN2CYP19A1HTTMEN1KMT2A | |
| SCHEMBL222384 | 0.88 | SMN1; SMN2 (0.58) | SMN1; SMN2CYP19A1HTTMEN1KMT2A | |
| SCHEMBL11650456 | 0.88 | TSHR (0.57) | SMN1; SMN2CYP19A1HTTMEN1KMT2A | |
| SCHEMBL11257538 | 0.87 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP19A1HTTMEN1KMT2A | |
| SCHEMBL10661602 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP19A1HTTMEN1KMT2A | |
| SCHEMBL3128740 | 0.87 | MEN1 (0.58) | SMN1; SMN2CYP19A1HTTMEN1KMT2A | |
| SCHEMBL6151007 | 0.87 | RAB9A (0.58) | SMN1; SMN2CYP19A1HTTMEN1KMT2A | |
| SCHEMBL11412235 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2CYP19A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775689-B9 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2004-09-15 | — | — | EP | disclosed |
| EP-0775689-B1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2003-09-03 | — | — | EP | disclosed |
| US-6057358-A | POTASSIUM CHANNEL BLOCKING ANTIARRHYTHMIC DRUGS WITH LESS SIDE EFFECTS | C&C RESEARCH LABS. (KR) | 2000-05-02 | — | — | US | disclosed |
| EP-0775689-A1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RESEARCH LABS. (KR) | 1997-05-28 | — | — | EP | disclosed |