Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661991 | 0.80 | — | — | |
| SCHEMBL4661900 | 0.78 | CYP2C19 (0.32) | — | |
| SCHEMBL4660714 | 0.78 | CYP2C19 (0.32) | — | |
| SCHEMBL4660712 | 0.78 | CYP2C19 (0.32) | — | |
| SCHEMBL4662128 | 0.78 | CYP2C19 (0.32) | — | |
| SCHEMBL4661890 | 0.78 | CYP2C19 (0.32) | — | |
| SCHEMBL4068123 | 0.76 | — | — | |
| SCHEMBL21582055 | 0.72 | — | — | |
| SCHEMBL28399152 | 0.72 | — | — | |
| SCHEMBL16684930 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280760-B1 | NOVEL SPIRO[2.4]HEPTANE AMINO CARBOXY COMPOUNDS AND DERIVATIVES THEREOF | CURRY KENNETH (CA) | 2004-04-28 | — | — | EP | disclosed |
| EP-1280760-B1 | NOVEL SPIRO[2.4]HEPTANE AMINO CARBOXY COMPOUNDS AND DERIVATIVES THEREOF | CURRY KENNETH (CA) | 2004-04-28 | — | — | EP | disclosed |
| US-20040077599-A1 | Novel spiro[2.4]heptane amino carboxy compounds and derivatives thereof | CURRY KENNETH (CA) | 2004-04-22 | — | — | US | disclosed |
| US-20040077599-A1 | Novel spiro[2.4]heptane amino carboxy compounds and derivatives thereof | CURRY KENNETH (CA) | 2004-04-22 | — | — | US | disclosed |
| EP-1280760-A1 | NOVEL SPIRO[2.4]HEPTANE AMINO CARBOXY COMPOUNDS AND DERIVATIVES THEREOF | Curry, Kenneth (CA) | 2003-02-05 | — | — | EP | disclosed |
| EP-1280760-A1 | NOVEL SPIRO[2.4]HEPTANE AMINO CARBOXY COMPOUNDS AND DERIVATIVES THEREOF | Curry, Kenneth (CA) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001085669-A1 | NOVEL SPIRO[2.4]HEPTANE AMINO CARBOXY COMPOUNDS AND DERIVATIVES THEREOF | CURRY KENNETH (CA) | 2001-11-15 | — | — | WO | disclosed |
| WO-2001085669-A1 | NOVEL SPIRO[2.4]HEPTANE AMINO CARBOXY COMPOUNDS AND DERIVATIVES THEREOF | CURRY KENNETH (CA) | 2001-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077599-A1 | Novel spiro[2.4]heptane amino carboxy compounds and derivatives thereof | GRM2, GRM1, GRIA2 | ATM 4045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.