Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4662128 | 1.00 | CYP2C19 (0.32) | CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL4661900 | 1.00 | CYP2C19 (0.32) | CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL4660714 | 1.00 | CYP2C19 (0.32) | CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL4661890 | 1.00 | CYP2C19 (0.32) | CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL4661991 | 0.98 | — | — | |
| SCHEMBL4068123 | 0.93 | — | — | |
| SCHEMBL6576415 | 0.78 | ATM (0.31) | — | |
| SCHEMBL16684930 | 0.74 | — | — | |
| SCHEMBL4661895 | 0.74 | — | — | |
| SCHEMBL4662020 | 0.74 | MAPT (0.32) | CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558230-B1 | SPIROCYCLOPROPYL AMIDES AND ACIDS AND THEIR THERAPEUTIC APPLICATIONS | ABBOTT LAB (US) | 2008-12-31 | — | — | EP | claimed |