⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18563324 | 0.77 | OPRM1 (0.33) | — | |
| SCHEMBL18502945 | 0.77 | OPRM1 (0.33) | — | |
| SCHEMBL15886182 | 0.77 | OPRM1 (0.33) | — | |
| SCHEMBL21827766 | 0.71 | — | — | |
| SCHEMBL6576552 | 0.69 | ESR2 (0.33) | — | |
| SCHEMBL26121502 | 0.69 | — | — | |
| SCHEMBL12134925 | 0.69 | — | — | |
| SCHEMBL28987487 | 0.68 | TSHR (0.38) | — | |
| SCHEMBL8977695 | 0.68 | NR1I3 (0.36) | — | |
| Hydrochloric Acid SCHEMBL26121074 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889726-B1 | NOVEL CYCLOALKYL SUBSTITUTED IMIDAZOLES | SMITHKLINE BEECHAM CORP (US) | 2004-09-15 | — | — | EP | disclosed |
| EP-0900083-B1 | NOVEL SUBSTITUTED IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2003-08-20 | — | — | EP | disclosed |
| EP-1314728-A1 | Pyridyl and pyrimidinyl imines as intermediates for imidazole derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 2003-05-28 | — | — | EP | disclosed |
| EP-0831830-B1 | IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6329526-B1 | Cycloalkyl substituted imidazoles | SMITHKLINE BEECHAM CORPORATION | 2001-12-11 | — | — | US | disclosed |
| US-6251914-B1 | TREATING CYTOKINE MEDIATED DISEASES | SMITHKLINE BEECHAM CORPORATION | 2001-06-26 | — | — | US | disclosed |
| US-6218537-B1 | Process for making pyridyl and pyrimidine substituted imidazole compounds | SMITHKLINE BEECHAM CORPORATION | 2001-04-17 | — | — | US | disclosed |
| EP-0802908-A4 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-1019396-A1 | NOVEL CYCLOALKYL SUBSTITUTED IMIDAZOLES | SmithKline Beecham Corporation (US) | 2000-07-19 | — | — | EP | disclosed |
| US-5977103-A | Substituted imidazole compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0883402-A1 | NOVEL CYCLOALKYL SUBSTITUDED IMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1998-12-16 | — | — | EP | disclosed |
| CN-1192147-A | Imidazole compounds | SMITHKLINE BEECHAM CORP (US) | 1998-09-02 | — | — | CN | disclosed |
| US-5756499-A | Substituted imidazole compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| US-5739143-A | Imidazole compounds and compositions | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-14 | — | — | US | disclosed |
| EP-0802908-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-29 | — | — | EP | disclosed |
| US-5658903-A | Imidazole compounds, compositions and use | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |
| WO-1997025047-A1 | NOVEL CYCLOALKYL SUBSTITUDED IMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |
| WO-1997025045-A1 | NOVEL SUBSTITUTED IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |
| WO-1997025048-A1 | NOVEL CYCLOALKYL SUBSTITUTED IMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |
| WO-1996021654-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-07-18 | — | — | WO | disclosed |