Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.50 |
| ▸ | CA12 | O43570 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 6/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA4 | P22748 | 6/20 | 0.50 |
| ▸ | CA7 | P43166 | 6/20 | 0.50 |
| ▸ | CA9 | Q16790 | 6/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756950 | 0.93 | KDM4E (0.60) | KDM4EABL1LMNAGPR119HRH3 | |
| SCHEMBL760736 | 0.85 | KDM4E (0.52) | KDM4EABL1LMNAGPR119TRPV1 | |
| SCHEMBL760738 | 0.85 | KDM4E (0.52) | KDM4EABL1LMNAGPR119TRPV1 | |
| SCHEMBL760735 | 0.85 | KDM4E (0.52) | KDM4EABL1LMNAGPR119TRPV1 | |
| SCHEMBL30549242 | 0.79 | GPR119 (0.49) | KDM4EABL1LMNAGPR119CHRM2 | |
| SCHEMBL7250781 | 0.79 | KDM4E (0.58) | KDM4EABL1LMNAGPR119TRPV1 | |
| SCHEMBL1103853 | 0.78 | KDM4E (0.64) | KDM4EABL1LMNAGPR119HRH3 | |
| SCHEMBL24008720 | 0.78 | KDM4E (0.51) | KDM4EABL1LMNATRPV1HRH3 | |
| SCHEMBL12419695 | 0.77 | KDM4E (0.62) | KDM4EABL1LMNAGPR119HRH3 | |
| SCHEMBL30233640 | 0.77 | KDM4E (0.62) | KDM4EABL1LMNAGPR119HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392690-A2 | NOVEL PROCESSES FOR THE PREPARATION OF ADENOSINE COMPOUNDS AND INTERMEDIATES THERETO | Aventis Pharma Deutschland GmbH (DE) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002091988-A2 | NOVEL PROCESSES FOR THE PREPARATION OF ADENOSINE COMPOUNDS AND INTERMEDIATES THERETO | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-11-21 | — | — | WO | disclosed |