Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576701 | 1.00 | ADORA1 (0.53) | ADORA1ADORA3ADORA2AADORA2BPMP22 | |
| SCHEMBL6573833 | 0.91 | ADORA1 (0.55) | ADORA1ADORA3ADORA2AADORA2BPMP22 | |
| SCHEMBL6573828 | 0.91 | ADORA1 (0.55) | ADORA1ADORA3ADORA2AADORA2BPMP22 | |
| SCHEMBL6574536 | 0.89 | ADORA1 (0.53) | ADORA1ADORA3ADORA2AADORA2BPMP22 | |
| SCHEMBL6574533 | 0.89 | ADORA1 (0.53) | ADORA1ADORA3ADORA2AADORA2BPMP22 | |
| SCHEMBL6576787 | 0.89 | ADORA3 (0.58) | ADORA1ADORA3ADORA2AADORA2BPMP22 | |
| SCHEMBL6576840 | 0.88 | ADORA1 (0.55) | ADORA1ADORA3ADORA2AADORA2BPMP22 | |
| SCHEMBL6576844 | 0.88 | ADORA1 (0.55) | ADORA1ADORA3ADORA2AADORA2BPMP22 | |
| SCHEMBL6881499 | 0.86 | ADORA1 (0.53) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL6575148 | 0.86 | ADORA1 (0.53) | ADORA1ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | disclosed |
| EP-1447407-A1 | Adenosine derivatives | GLAXO GROUP LIMITED (GB) | 2004-08-18 | — | — | EP | disclosed |