Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576816 | 1.00 | TRPV1 (0.38) | TRPV1LMNAMEN1NPC1ALDH1A1 | |
| SCHEMBL6578891 | 0.92 | MAOB (0.38) | TRPV1ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL6578885 | 0.92 | MAOB (0.38) | TRPV1ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL6579381 | 0.90 | ALDH1A1 (0.35) | TRPV1LMNANPC1ALDH1A1MAPT | |
| SCHEMBL6579376 | 0.90 | ALDH1A1 (0.35) | TRPV1LMNANPC1ALDH1A1MAPT | |
| SCHEMBL6579348 | 0.85 | SMN1; SMN2 (0.45) | TRPV1LMNAMEN1ALDH1A1MAPT | |
| SCHEMBL6579338 | 0.85 | SMN1; SMN2 (0.45) | TRPV1LMNAMEN1ALDH1A1MAPT | |
| SCHEMBL6579384 | 0.84 | TRPV1 (0.39) | TRPV1ALDH1A1ALOX15 | |
| SCHEMBL6579387 | 0.84 | TRPV1 (0.39) | TRPV1ALDH1A1ALOX15 | |
| SCHEMBL6581186 | 0.83 | TRPV1 (0.43) | TRPV1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |