Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997377 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6578917 | 0.85 | KMT2A (0.70) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6578987 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2KMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL6581064 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2KMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL6581538 | 0.82 | SMN1; SMN2 (0.76) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7305473 | 0.81 | SMN1; SMN2 (0.71) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9495805 | 0.81 | KMT2A (0.72) | SMN1; SMN2KMT2AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL38661106 | 0.80 | KMT2A (0.74) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6169051 | 0.79 | SMN1; SMN2 (0.86) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6790086 | 0.79 | KMT2A (0.72) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |