Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | GALR2 | O43603 | 1/20 | 0.68 |
| ▸ | MITF | O75030 | 1/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.68 |
| ▸ | XBP1 | P17861 | 1/20 | 0.68 |
| ▸ | CCR6 | P51684 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169051 | 0.93 | SMN1; SMN2 (0.86) | SMN1; SMN2ALDH1A1LMNAPOLBHPGD | |
| SCHEMBL6581538 | 0.86 | SMN1; SMN2 (0.76) | SMN1; SMN2ALDH1A1LMNAPOLBHPGD | |
| SCHEMBL3606284 | 0.86 | SMN1; SMN2 (0.76) | SMN1; SMN2ALDH1A1LMNAPOLBHPGD | |
| SCHEMBL11450353 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2ALDH1A1LMNAPOLBHPGD | |
| SCHEMBL6576971 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2ALDH1A1POLBHPGDKMT2A | |
| SCHEMBL8004123 | 0.85 | SMN1; SMN2 (0.73) | SMN1; SMN2ALDH1A1LMNAPOLBHPGD | |
| SCHEMBL7305473 | 0.83 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1LMNAPOLBHPGD | |
| SCHEMBL6171928 | 0.82 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1LMNAPOLBHPGD | |
| SCHEMBL7723906 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL26687978 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1LMNAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |