Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5635312 | 0.75 | SLC6A2 (0.34) | CYP1A2CYP2D6CYP3A4CYP2C9LMNA | |
| Hydrochloric Acid SCHEMBL5634885 | 0.73 | LMNA (0.35) | CYP1A2CYP2D6CYP3A4CYP2C9LMNA | |
| SCHEMBL5635776 | 0.73 | CHRM1 (0.33) | CYP1A2CYP2D6CYP3A4CYP2C9LMNA | |
| SCHEMBL5637614 | 0.72 | CHRM1 (0.35) | CYP1A2CYP2D6CYP3A4CYP2C9LMNA | |
| SCHEMBL5636611 | 0.71 | CHRM3 (0.37) | CYP1A2CYP2D6CYP3A4CYP2C9LMNA | |
| SCHEMBL6574874 | 0.70 | MEN1 (0.35) | CYP1A2CYP2D6CYP3A4LMNAMAPT | |
| SCHEMBL5664764 | 0.70 | PDE7A (0.41) | CYP3A4MAPTSLC6A2CHRM1SLC6A4 | |
| SCHEMBL14573390 | 0.70 | PDE7A (0.41) | CYP3A4MAPTSLC6A2CHRM1SLC6A4 | |
| SCHEMBL5636317 | 0.69 | SLC6A2 (0.39) | CYP1A2CYP2D6SLC6A2CHRM1SLC6A4 | |
| SCHEMBL5636304 | 0.68 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472248-A1 | MODULATORS OF ACETYLCHOLINE RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003062235-A1 | MODULATORS OF ACETYLCHOLINE RECEPTORS | ELI LILLY AND COMPANY (US) | 2003-07-31 | — | — | WO | disclosed |