Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577074 | 1.00 | ALDH2 (0.40) | ALDH2NR5A1ALDH1A1KDM4EHPGD | |
| SCHEMBL6578986 | 0.90 | CNR2 (0.38) | ALDH2NR5A1ALDH1A1KDM4EHPGD | |
| SCHEMBL6578979 | 0.90 | CNR2 (0.38) | ALDH2NR5A1ALDH1A1KDM4EHPGD | |
| SCHEMBL6581339 | 0.89 | CNR2 (0.40) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL6581346 | 0.89 | CNR2 (0.40) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL6579786 | 0.87 | CNR2 (0.39) | ALDH1A1KDM4EHPGDHSD17B10CNR2 | |
| SCHEMBL6579794 | 0.87 | CNR2 (0.39) | ALDH1A1KDM4EHPGDHSD17B10CNR2 | |
| SCHEMBL6582135 | 0.82 | CNR1 (0.39) | ALDH1A1KDM4ETP53MEN1GAA | |
| SCHEMBL6582132 | 0.82 | CNR1 (0.39) | ALDH1A1KDM4ETP53MEN1GAA | |
| SCHEMBL6277838 | 0.79 | KDM4E (0.41) | ALDH2NR5A1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |