Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | RORA | P35398 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | RORB | Q92753 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579794 | 1.00 | CNR2 (0.39) | CNR2RORARORCRORBSERPINE1 | |
| SCHEMBL6578979 | 0.88 | CNR2 (0.38) | CNR2CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL6578986 | 0.88 | CNR2 (0.38) | CNR2CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL6577074 | 0.87 | ALDH2 (0.40) | CNR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6581339 | 0.87 | CNR2 (0.40) | CNR2RORARORCRORBKDM4E | |
| SCHEMBL6581346 | 0.87 | CNR2 (0.40) | CNR2RORARORCRORBKDM4E | |
| SCHEMBL6577064 | 0.87 | ALDH2 (0.40) | CNR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6579027 | 0.82 | LMNA (0.40) | CNR2RORARORCRORBCNR1 | |
| SCHEMBL6582135 | 0.78 | CNR1 (0.39) | CNR2CNR1KDM4EALDH1A1LMNA | |
| SCHEMBL6582132 | 0.78 | CNR1 (0.39) | CNR2CNR1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |