Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329730 | 1.00 | CASP1 (0.48) | CASP1CA2CTRB1TRPM8PPARA | |
| SCHEMBL7594853 | 1.00 | CASP1 (0.48) | CASP1CA2CTRB1TRPM8PPARA | |
| SCHEMBL6577081 | 1.00 | CASP1 (0.48) | CASP1CA2CTRB1TRPM8PPARA | |
| SCHEMBL6328905 | 1.00 | CASP1 (0.48) | CASP1CA2CTRB1TRPM8PPARA | |
| SCHEMBL7491284 | 1.00 | CASP1 (0.48) | CASP1CA2CTRB1TRPM8PPARA | |
| SCHEMBL6579034 | 0.91 | CASP1 (0.51) | CASP1CA2CTRB1TRPM8PPARA | |
| SCHEMBL6578643 | 0.91 | CASP1 (0.51) | CASP1CA2CTRB1TRPM8PPARA | |
| SCHEMBL14583738 | 0.89 | CASP1 (0.49) | CASP1CA2CTRB1TRPM8PPARA | |
| SCHEMBL14583750 | 0.89 | CASP1 (0.49) | CASP1CA2CTRB1TRPM8PPARA | |
| SCHEMBL14583752 | 0.89 | CASP1 (0.49) | CASP1CA2CTRB1TRPM8PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972760-B1 | PROCESS FOR THE PURIFICATION OR ISOLATION OF (2S, 3R)-1-HALO-2-HYDROXY-3-(PROTECTED AMINO)-4-PHENYLTHIOBUTANES OR OPTICAL ANTIPODES THEREOF | KANEKA CORP (JP) | 2004-09-22 | — | — | EP | disclosed |
| EP-0969000-B1 | Process for reducing alpha-amino ketones | KANEKA CORP (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6255522-B1 | USING AS REDUCING AGENT A REACTION PRODUCT OF ORGANOALUMINUM COMPOUND, SULFONATE AND ALCOHOL | KANEKA CORPORATION (JP) | 2001-07-03 | — | — | US | disclosed |
| US-6107511-A | Process for the purification or isolation of (2S,3R)-1-halo-2-hydroxy-3-(protected amino)4-phenylthiobutanes or optical antipodes thereof | KANEKA CORPORATION (JP) | 2000-08-22 | — | — | US | disclosed |
| EP-0972760-A1 | PROCESS FOR THE PURIFICATION OR ISOLATION OF (2S, 3R)-1-HALO-2-HYDROXY-3-(PROTECTED AMINO)-4-PHENYLTHIOBUTANES OR OPTICAL ANTIPODES THEREOF | KANEKA CORPORATION (JP) | 2000-01-19 | — | — | EP | disclosed |
| EP-0969000-A1 | PROCESS FOR REDUCING $G(a)-AMINO KETONES | KANEKA CORPORATION (JP) | 2000-01-05 | — | — | EP | disclosed |