Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 17/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 17/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4887639 | 0.96 | VDR (0.52) | VDRNR1H2NR1H3NR1I2MLYCD | |
| SCHEMBL4884687 | 0.96 | VDR (0.52) | VDRNR1H2NR1H3MLYCD | |
| SCHEMBL4891361 | 0.89 | VDR (0.53) | VDRNR1H2NR1H3NR1I2MLYCD | |
| SCHEMBL4888589 | 0.88 | VDR (0.58) | VDRNR1H2NR1H3NR1I2 | |
| SCHEMBL4893090 | 0.88 | VDR (0.58) | VDRNR1H2NR1H3NR1I2 | |
| SCHEMBL4895050 | 0.86 | VDR (0.65) | VDRNR1H2NR1H3NR1I2 | |
| SCHEMBL6579160 | 0.85 | VDR (0.60) | VDRNR1H2NR1H3NR1I2MLYCD | |
| SCHEMBL4892735 | 0.85 | VDR (0.66) | VDR | |
| SCHEMBL4886580 | 0.83 | VDR (0.63) | VDRNR1H2NR1H3 | |
| SCHEMBL2640259 | 0.83 | VDR (0.67) | VDRNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456160-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003050067-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, SNC (FR) | 2003-06-19 | — | — | WO | disclosed |