Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575124 | 0.85 | GAA (0.49) | KDM4EGAAHSD17B10NPSR1PPARA | |
| SCHEMBL6809898 | 0.84 | ALDH1A1 (0.51) | KDM4EGAAHSD17B10NPSR1PPARA | |
| SCHEMBL17973238 | 0.83 | KDM4E (0.57) | KDM4EGAAHSD17B10NPSR1PPARA | |
| SCHEMBL6579492 | 0.82 | POLB (0.52) | KDM4EPPARAPPARGHPGDALDH1A1 | |
| SCHEMBL16569366 | 0.82 | KDM4E (0.53) | KDM4EGAAHSD17B10NPSR1PPARA | |
| SCHEMBL8251631 | 0.81 | GAA (0.56) | KDM4EGAAHSD17B10NPSR1PPARA | |
| SCHEMBL6813349 | 0.81 | ABCB1 (0.41) | GAANPSR1PPARAPPARGHPGD | |
| SCHEMBL27780118 | 0.80 | ABCB1 (0.46) | GAANPSR1HPGDALDH1A1MAPT | |
| SCHEMBL903866 | 0.79 | GAA (0.53) | KDM4EGAAHSD17B10NPSR1PPARA | |
| SCHEMBL1257644 | 0.79 | KDM4E (0.56) | KDM4EGAAHSD17B10NPSR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002791-B1 | AMINOETHYLPHENOXYACETIC ACID DERIVATIVES AND DRUGS FOR PAIN REMISSION AND CALCULI REMOVAL PROMOTION IN URINARY LITHIASIS | KISSEI PHARMACEUTICAL (JP) | 2004-10-20 | — | — | EP | disclosed |
| US-6399660-B1 | AMINOETHYLPHENOXYACETIC ACID COMPOUND | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| EP-1002791-A1 | AMINOETHYLPHENOXYACETIC ACID DERIVATIVES AND DRUGS FOR PAIN REMISSION AND CALCULI REMOVAL PROMOTION IN URINARY LITHIASIS | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-05-24 | — | — | EP | disclosed |