SCHEMBL6577843

SCHEMBL6577843

C1=CC([Zr]C2C=Cc3ccccc32)c2ccccc21.C[SiH2]C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.35
HTR6 P50406 1/20 0.35
SIGMAR1 Q99720 6/20 0.33
KDM4E B2RXH2 2/20 0.33
BRD4 O60885 1/20 0.33
CCL2 P13500 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CHRM2 P08172 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
NFKB1 P19838 1/20 0.33
CHRM3 P20309 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60674 0.92 HTR2A (0.40) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL29474414 0.92 HTR2A (0.40) HTR2AHTR6SIGMAR1KDM4EBRD4
Fluoromethane SCHEMBL8734234 0.90 HTR2A (0.36) HTR2AHTR6SIGMAR1KDM4EBRD4
Chloromethane SCHEMBL3681238 0.90 HTR2A (0.36) HTR2AHTR6SIGMAR1KDM4EBRD4
Methane SCHEMBL5838564 0.90 HTR2A (0.39) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL27597712 0.90 HTR2A (0.39) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL28278996 0.90 HTR2A (0.39) HTR2AHTR6SIGMAR1KDM4EBRD4
Hydrochloric Acid SCHEMBL5838117 0.90 HTR2A (0.39) HTR2AHTR6SIGMAR1KDM4EBRD4
Hydrochloric Acid SCHEMBL8033537 0.88 HTR2A (0.35) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL28300114 0.88 HTR2A (0.35) HTR2AHTR6SIGMAR1KDM4EBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1056752-B1 Catalyst activators comprising expanded anions DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-25 EP claimed
US-20140200317-A1 Methods for Reducing Static Charge of a Catalyst and Methods for Using the Catalyst to Produce Polyolefins UNIVATION TECHNOLOGIES, LLC (US) 2014-07-17 US disclosed
US-8722820-B2 Methods for reducing static charge of a catalyst and methods for using the catalyst to produce polyolefins UNIVATION TECHNOLOGIES, LLC (US) 2014-05-13 US disclosed
US-20130085245-A1 Methods for Reducing Static Charge of a Catalyst and Methods for Using the Catalyst to Produce Polyolefins UNIVATION TECHNOLOGIES, LLC (US) 2013-04-04 US disclosed
EP-1412365-A1 SALT OF LEWIS ACID/ACID ADDUCTS AND CATALYST ACTIVATORS THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2004-04-28 EP disclosed
EP-1401897-A1 ALPHA-OLEFIN BASED BRANCHED POLYMER DOW GLOBAL TECHNOLOGIES INC. (US) 2004-03-31 EP disclosed
WO-2003010171-A1 SALT OF LEWIS ACID/ACID ADDUCTS AND CATALYST ACTIVATORS THEREFROM DOW GLOBAL TECHNOLOGIES, INC. (US) 2003-02-06 WO disclosed
WO-2002102863-A1 ALPHA-OLEFIN BASED BRANCHED POLYMER DOW GLOBAL TECHNOLOGIES INC. (US) 2002-12-27 WO disclosed
US-20010027161-A1 Catalyst activators comprising expanded anions THE DOW CHEMICAL COMPANY 2001-10-04 US disclosed