Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 10/20 | 0.80 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.80 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.80 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.80 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.80 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3411560 | 0.93 | CHRM1 (0.70) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL13243458 | 0.93 | CHRM1 (0.70) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL6580000 | 0.92 | CHRM1 (0.69) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL6580671 | 0.92 | CHRM1 (0.69) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL6580373 | 0.89 | CHRM1 (1.00) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL6580262 | 0.88 | CHRM1 (0.76) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL6577611 | 0.86 | CHRM1 (0.63) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL5476462 | 0.85 | CHRM1 (0.76) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL8863392 | 0.85 | CHRM1 (0.69) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL6577844 | 0.85 | HSD11B1 (0.62) | CHRM1CHRM2CHRM4CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1221443-B1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |