Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29751652 | 0.85 | KDM4E (0.39) | MAPTALDH1A1TSHRMAPK1ACE2 | |
| SCHEMBL125462 | 0.84 | KDM4E (0.46) | MAPTALDH1A1TSHRMAPK1ACE2 | |
| SCHEMBL8581242 | 0.83 | MAPT (0.44) | MAPTALDH1A1TSHRMAPK1ACE2 | |
| SCHEMBL29111402 | 0.82 | SERPINE1 (0.46) | MAPTALDH1A1TSHRMAPK1ADRB2 | |
| SCHEMBL9807482 | 0.81 | MAPT (0.37) | MAPTALDH1A1TSHRMAPK1ACE2 | |
| SCHEMBL351318 | 0.76 | MAPT (0.64) | MAPTALDH1A1TSHRADRB2ADRB1 | |
| SCHEMBL29162948 | 0.74 | MAPT (0.62) | MAPTALDH1A1TSHRADRB2ADRB1 | |
| SCHEMBL9417452 | 0.74 | KDM4E (0.47) | MAPTALDH1A1TSHRMAPK1ACE2 | |
| SCHEMBL11766135 | 0.74 | ALDH1A1 (0.36) | MAPTALDH1A1TSHRMAPK1ADRB2 | |
| SCHEMBL11516863 | 0.74 | ALDH1A1 (0.45) | MAPTALDH1A1TSHRMAPK1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926178-B1 | Method to reduce gel formation in PET resin | ARTEVA TECH SARL (CH) | 2004-05-06 | — | — | EP | claimed |
| EP-0926178-A1 | Method to reduce gel formation in PET resin | HNA Holdings, Inc. (US) | 1999-06-30 | — | — | EP | claimed |
| EP-0926179-A2 | Method to reduce regenerated acetaldehyde in polyester resins | HNA Holdings, Inc. (US) | 1999-06-30 | — | — | EP | claimed |
| US-5874515-A | CATALYTIC ESTER INTERCHANGE | HOECHST CELANESE CORPORATION (US) | 1999-02-23 | — | — | US | claimed |
| US-5874517-A | ADDITION OF PRIMARY PHENOLIC AND SECONDARY PHOSPHONITE ANTIOXIDANTS EITHER PRIOR TO OR AFTER THE POLYETHYLENE TEREPHTHALATE POLYCONDENSATION REACTION IN ORDER TO REDUCE THE AMOUNT OF REGENERATED ACETALDEHYDE PRODUCED | HOECHST CELANESE CORPORATION (US) | 1999-02-23 | — | — | US | claimed |