⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439863 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL29050718 | 0.77 | TSHR (0.31) | — | |
| Bromide SCHEMBL15018257 | 0.77 | TSHR (0.31) | — | |
| Hydrochloric Acid SCHEMBL15018418 | 0.77 | TSHR (0.31) | — | |
| Water SCHEMBL28338535 | 0.77 | TSHR (0.31) | — | |
| SCHEMBL6578531 | 0.76 | — | — | |
| SCHEMBL8508514 | 0.73 | — | — | |
| SCHEMBL7763100 | 0.71 | — | — | |
| SCHEMBL8727735 | 0.71 | — | — | |
| SCHEMBL8531466 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261613-B1 | GASTRO-SPECIFIC PRODRUGS | PHARMACIA CORP (US) | 2004-05-06 | — | — | EP | disclosed |
| EP-1261613-A1 | GASTRO-SPECIFIC PRODRUGS | Pharmacia Corporation (US) | 2002-12-04 | — | — | EP | disclosed |
| US-6471955-B1 | POLYSTYRENES AS PREFERENTIAL TIME-RELEASE AGENTS OR CARRIERS OF PROSTAGLANDINS SUCH AS MISOPROSTOL USED FOR PREVENTION OF PEPTIC ULCERS | PHARMACIA CORPORATION | 2002-10-29 | — | — | US | disclosed |
| US-6413945-B1 | REACTION PRODUCT OF ORGANOSILICON COMPOUNDS AND DRUG; ANTIULCER AGENTS | PHARMACIA CORPORATION | 2002-07-02 | — | — | US | disclosed |
| WO-2001064690-A1 | GASTRO-SPECIFIC PRODRUGS | PHARMACIA CORPORATION (US) | 2001-09-07 | — | — | WO | disclosed |
| US-6030959-A | FOR TREATMENT AND PROPHYLAXIS OF GASTRIC ULCERS | MONSANTO COMPANY (US) | 2000-02-29 | — | — | US | disclosed |
| WO-1998044952-A1 | pH-SELECTIVE DELIVERY SYSTEM USING CROSS-LINKED POLYMERIC RESINS AS VEHICLES | MONSANTO COMPANY (US) | 1998-10-15 | — | — | WO | disclosed |
| EP-0305855-B1 | SYNTHESIS OF SILYL KETENE ACETAL FROM ALLYL 2-ORGANOACRYLATES | DOW CORNING CORPORATION (US) | 1993-09-15 | — | — | EP | disclosed |
| EP-0305855-A2 | Synthesis of silyl ketene acetal from allyl 2-organoacrylates | DOW CORNING CORPORATION (US) | 1989-03-08 | — | — | EP | disclosed |
| US-4746750-A | HYDROSILATION, CLEAVAGE OF PROPYLENE, REARRANGEMENTS | DOW CORNING CORPORATION (US) | 1988-05-24 | — | — | US | disclosed |