SCHEMBL6578053

SCHEMBL6578053

Cc1ccc(C(=O)OCCCCCCOC(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.62
NPC1 O15118 3/20 0.62
RAB9A P51151 3/20 0.62
ALDH1A1 P00352 3/20 0.62
MAPT P10636 2/20 0.62
TSHR P16473 3/20 0.58
ESR1 P03372 3/20 0.58
LMNA P02545 2/20 0.58
CYP1A2 P05177 2/20 0.58
CYP2C19 P33261 2/20 0.58
CYP2D6 P10635 1/20 0.58
MAPK1 P28482 1/20 0.58
NR1H2 P55055 1/20 0.58
RNASEL Q05823 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
CYP3A4 P08684 1/20 0.56
CYP2C9 P11712 1/20 0.56
PDE4D Q08499 1/20 0.56
HDAC6 Q9UBN7 1/20 0.54
STS P08842 5/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14984030 1.00 TDP1 (0.62) TDP1NPC1RAB9AALDH1A1MAPT
SCHEMBL6578044 0.98 TDP1 (0.64) TDP1NPC1RAB9AALDH1A1MAPT
SCHEMBL13410610 0.94 TSHR (0.59) TDP1NPC1RAB9AALDH1A1MAPT
SCHEMBL7519234 0.93 ALDH1A1 (0.73) NPC1RAB9AALDH1A1MAPTTSHR
SCHEMBL14926488 0.93 NPC1 (0.55) TDP1NPC1RAB9AALDH1A1MAPT
SCHEMBL6057197 0.93 ALDH1A1 (0.73) NPC1RAB9AALDH1A1MAPTTSHR
SCHEMBL14379757 0.93 NPC1 (0.55) TDP1NPC1RAB9AALDH1A1MAPT
SCHEMBL28807892 0.93 ALDH1A1 (0.73) NPC1RAB9AALDH1A1MAPTTSHR
SCHEMBL28816320 0.93 ALDH1A1 (0.73) NPC1RAB9AALDH1A1MAPTTSHR
SCHEMBL27889920 0.93 ALDH1A1 (0.73) NPC1RAB9AALDH1A1MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1067157-B1 Ink composition for a meltable ink and a method of printing a substrate with such an ink composition OCE TECH BV (NL) 2004-05-06 EP claimed
US-6471758-B1 SINGLE PACKAGE; SOLID AT ROOM TEMPERATURE AND FLUID WHEN HEATED; GELLING AGENT THAT INCREASES VISCOSITY TO FIX INK DROPS; POROUS AND SMOOTH SUBSTRATES; SUITABLE FOR THERMAL AFTERTREATMENT PRINTING OCE TECHNOLOGIES B.V. (NL) 2002-10-29 US claimed
EP-0086473-B2 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Montedison S.p.A. (IT) 1992-11-11 EP claimed
EP-0086473-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Montedison S.p.A. (IT) 1987-05-20 EP claimed
EP-2596960-B1 Reusable print medium and method of manufacturing thereof OCE TECH BV (NL) 2016-04-20 EP disclosed
US-8809432-B2 Reusable print medium and method of manufacturing thereof OCE TECHNOLOGIES B.V. (NL) 2014-08-19 US disclosed
US-8809432-B2 Reusable print medium and method of manufacturing thereof OCE TECHNOLOGIES B.V. (NL) 2014-08-19 US disclosed
EP-2748247-A1 POLYALKYLENE GLYCOL-DI-P-TOLUATES AND -BENZOATES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE Invista Technologies S.a r.l. (CH) 2014-07-02 EP disclosed
US-20130137805-A1 REUSABLE PRINT MEDIUM AND METHOD OF MANUFACTURING THEREOF OCE TECHNOLOGIES B.V. (NL) 2013-05-30 US disclosed
US-20130137805-A1 REUSABLE PRINT MEDIUM AND METHOD OF MANUFACTURING THEREOF OCE TECHNOLOGIES B.V. (NL) 2013-05-30 US disclosed
EP-2596960-A2 Reusable print medium and method of manufacturing thereof Océ-Technologies B.V. (NL) 2013-05-29 EP disclosed
WO-2013026917-A1 POLYALKYLENE GLYCOL-DI-P-TOLUATES AND -BENZOATES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE INVISTA TECHNOLOGIES S.À.R.L (CH) 2013-02-28 WO disclosed
US-6471758-B1 SINGLE PACKAGE; SOLID AT ROOM TEMPERATURE AND FLUID WHEN HEATED; GELLING AGENT THAT INCREASES VISCOSITY TO FIX INK DROPS; POROUS AND SMOOTH SUBSTRATES; SUITABLE FOR THERMAL AFTERTREATMENT PRINTING OCE TECHNOLOGIES B.V. (NL) 2002-10-29 US disclosed